The results of GEPIA database analysis suggested that TMEM200A was highly expressed in colon adenocarcinoma (CODA), esophageal carcinoma (ESCA), KIRC, KIRP, pancreatic adenocarcinoma (PADD), READ, STAD and thymoma (THYM) and low in adrenocortical carcinoma (ACC), cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), KICH, LUSC, ovarian serous cystadenocarcinoma (OV), UCEC, uterine carcinosarcoma (UCS) compared to normal tissues (Figure 1B). Here, TMEM200A is linked to familial cavitary optic disk anomaly.