The Venn diagramdemonstrated that ten genes, including HK2, VEGFA, IGFBP3, CAV1, ALOX5, CCND1,DIO1, NR3C2, ADH1B and PTGER3, are closely related to the differentiallyexpressed genes in the RCC cohort and SQDH targets genes (Figure 2(d)). Here, ADH1B is linked to renal cell carcinoma.