PDHA1 and neoplasm: The expression levels of these genes were compared between normal and tumor samples, and the results were shown in Figure 2(a); this showed that 13 genes, including ATP7A, NFE2L2, DLD, DBT, DLAT, DLST, FDX1, PDHA1, PDHB, MTF1, GLS, SLC31A1, and GCSH, were significantly downregulated in tumor tissues, while 3 genes, including ATP7B, NLRP3, and CDKN2A, were significantly upregulated (p < 0.001).