Firstly, we investigated the expression profile of PTPN1 at pancancer level via The Cancer Genome Atlas (TCGA) database and Clinical Proteomic Tumor Analysis Consortium (CPTAC) database, as well as the differential expression of PTPN1 in liver cancer from the International Cancer Genome Consortium (ICGC) database and the Human Protein Atlas (HPA) database. This evidence concerns the gene PTPN1 and neoplasm.