Relevant studies have shown that high expression of HSP90B1 usually predicts poor overall survival and disease-free survival of tumor patients, such as adrenal cortical carcinoma, renal papillary cell carcinoma, lung adenocarcinoma, and non-small cell lung cancer (NSCLC) (29, 30). The gene discussed is HSP90B1; the disease is non-small cell lung carcinoma.