LAMB3 and colorectal carcinoma: Taken together, we screened genes associated with radioresistance using sequencing data from HCT-116WT and HCT-116RR cells, and built a risk score model with five radioresistance genes, including TNFRSF13C, CD36, ANGPTL4, LAMB3, and SERPINA1. This risk score model showed favorable performance in prognosis prediction after radiotherapy for CRC.