In addition, we also find that the ratios of IL-6/IL-10 and IL-17/IL-10 vary with the clinical phase of BD and severity of symptoms: in BDD, the IL-6/IL-10 ratio decrease in mild BDD and the IL-17/IL-10 ratio decrease in severe BDD; while in BDM, the IL-6/IL-10 ratio elevate in mild BDM and decrease with the IL-17/IL-10 ratio in severe BDM. The gene discussed is IL6; the disease is Behcet disease.