As it has recently been revealed, different abnormal cardiac conditions such as coronary atherosclerosis, ventricular hypertrophy, and other ventricular filling abnormalities, heart failure, and even valvular heart diseases have underlying inflammatory etiologies accompanied by increased levels of inflammatory responses and thus CRP may have a major role to predict various types of cardiovascular diseases even in healthy subjects (6,7). This evidence concerns the gene CRP and heart valve disorder.