Additionally, pro- and anti-inflammatory cytokines/chemokines involved in tumor cell migration and progression such as interleukin 2 (IL-2), interleukin 4 (IL-4), interleukin 10 (IL-10), interleukin 18 (IL-18), interleukin 33 (IL-33), tumor necrosis factor alpha (TNF-α), transforming growth factor-beta (TGF-β) and macrophage colony-stimulating factor (M-CSF) have been reported to be preferentially enriched within exosomes (30–32). This evidence concerns the gene TGFB1 and neoplasm.