These transcriptomic analyses evidenced elevated quantities of TGF-β transcripts in some human tumors (red), such as glioblastoma (GBM), lower grade glioma (LGG) or head and neck squamous cell carcinoma (HNSC), as compared to associated normal tissues (green) (Figure 1A). Here, TGFB1 is linked to head and neck squamous cell carcinoma.