In total, 37 families consisting of 101 individuals were recruited within 2 years, including 11 children with cured BCP-ALL and ETV6::RUNX1 fusion with their parents, 8 children with cured high-hyperdiploid BCP-ALL with their parents and 18 healthy children with their parents (Suppl. The gene discussed is RUNX1; the disease is acute lymphoblastic leukemia.