TOP2A and hepatocellular carcinoma: Xue et al. (2022) identified a novel seven-ARG risk signature to predict prognoses of pancreatic adenocarcinoma. Compared with it, our prognosis model has higher precision. The ARGs that overlap our prognostic model with its model are PLAU and TOP2A. In addition, PLAU has predictive value as ARG in breast cancer, lung square cancer, head and neck square cell cancer, etc (Yang et al., 2020; Lv et al., 2021; Zhai et al., 2022). TOP2A can predict the prognosis of hepatocellular carcinoma (Cai et al., 2022).