More strikingly, we found the level of UNC93B1 expression was positively corelated with macrophages (r = 0.572, p < 0.001), and regulatory T cells (Tregs, r = 0.41, p < 0.001) in AML (Figure 5E), which were responsible for suppressing functional T cell activation and regulating immune systems. The gene discussed is UNC93B1; the disease is acute myeloid leukemia.