Further analysis of RNA sequencing data from The Cancer Genome Atlas (TCGA) for 179 PAAD samples and 171 normal pancreas samples interrogated that TRIM69 was upregulated in PAAD tissues, in concert with the upregulation of Ctnnb1 and Id2 (Supplemental Figure 4B). This evidence concerns the gene CTNNB1 and pancreatic adenocarcinoma.