Finally, 14 TFs (NOTCH3, NR5A1, WDR5, RARB, SRCAP, MTA2, ONECUT1, PITX3, TRAF6, SMAD3, JDP2, FOSL1, GLI1, MTF1) were found to be significantly related to RFS in GC patients by multivariate Cox analysis. Here, ONECUT1 is linked to gastric cancer.