For instance, miR-429 inhibits cell metastasis and invasion and reverses TGF-β-associated epithelial-to-mesenchymal transition (EMT) in colorectal cancer, and can reverse the changes in related marker genes induced by TGF-β in EMT, including CTNNA1 (Fig. 1A) 24. The gene discussed is TGFB1; the disease is colorectal cancer.