In recent years, lncRNA UCA1 has been reported to be the most abundant isoform in various malignant tumors, such as bladder cancer, breast cancer, hepatocellular carcinoma and pancreatic cancer, and play an important role in tumor invasion and metastasis, angiogenesis, immune escape and chemotherapeutic drug resistance 17, 20-30. This evidence concerns the gene UCA1 and familial pancreatic carcinoma.