Previously, we have shown that the expressions of leucocyte antigen related protein tyrosine phosphatase-interacting protein (liprin)-α4, master-mind like 3 (MAML3), recombination signal binding protein for immunoglobulin kappa J region (RBPL) and family with sequence similarity 115, member C (FAM115C) increased under hypoxic conditions in pancreatic cancer. This evidence concerns the gene TCAF2 and familial pancreatic carcinoma.