The results of CCK-8 and EdU assays have indicated that the administration of rSEMA5A could significantly enhance the proliferation ability of PLXNB3-overexpressed tumor cell AsPC1PLXNB3-OE, while this effect would be lost once TSP domain was cut off (Figures 4(g) and 4(h)). Here, PLXNB3 is linked to neoplasm.