The draft conceptual model reported here, while not drawn from a comprehensive set of qualitative interviews, reflects current understanding of the neurodevelopmental disorders and developmental epileptic encephalopathies (DEE) caused by mutations in SLC6A1, based upon all cases reported in the published literature, supplemented by an analysis of interactions between caregivers on social media, and interviews with two KOLs. Here, SLC6A1 is linked to neurodevelopmental disorder.