Although hyperlipidemia and disturbed blood flow can also promote NFκB activation and expression of inflammatory cytokines and leukocyte adhesion molecules, endothelial cell VE‐PTP deletion in ApoE−/−/VE‐PTPiECKO mice was not accompanied by changes in ICAM1 or VCAM1 in aortic endothelial cells. This evidence concerns the gene VCAM1 and hyperlipidemia.