Compared to wild-type mice, FXR-deficient mice exhibit reduced recruitment of inflammatory cells during DSS-induced colitis.89 Mice receiving CDCA supplementation exhibit decreased recruitment of monocytes/macrophages and neutrophils to the intestinal mucosa, whereas the relative amount of B cells is elevated during infection with S. Typhimurium and C. rodentium. This evidence concerns the gene NR1H4 and infection.