In addition, in chronic obstructive pulmonary disease (COPD) mouse model and CSE-induced human bronchial epithelial (HBE) cells, TAX conferred beneficial effects via attenuating oxidative stress and reducing expressions of iron death-related proteins, such as glutathione peroxidase 4 (GPX4) and solute carrier family 7 member 11 (SLC7A11) [87]. Here, GPX4 is linked to chronic obstructive pulmonary disease.