Interestingly, this dysregulation appears to differentially affect homologues and functionally related genes: for example, SNAI1, which encodes the SNAIL transcription factor, a major effector of the stem‐like phenotype in multiple cancer types,81, 82 is found to be upregulated, while its homologue with shared functionality within cancer, SNAI283 (encoding SLUG) is downregulated on BAP1 loss (Figure 4E). Here, SNAI2 is linked to cancer.