Moreover, compared with grp‐E (left glioma, 0.334 ± 0.019; right glioma, 0.396 ± 0.033), global efficiency was weaker in grp‐nE (left glioma, 0.277 ± 0.005, p = 0.0057; right glioma, 0.288 ± 0.014, p = 0.0064) and grp‐GnE (left glioma, 0.278 ± 0.013, p = 0.0452; right glioma, 0.274 ± 0.009, p = 0.0047). The gene discussed is GRPEL1; the disease is central nervous system cancer.