ATF4, a member of the ATF/CREB family of transcription factors, is involved in supporting the survival of cancer cells undergoing external pressure, such as MYC‐induced stress.[23, 24] Our data indicated that ATF4 mRNA expression levels were elevated in cytotoxin‐induced 4TO7 NDCs (Figure S3F, Supporting Information) and primary or metastatic tumor tissues derived from cytotoxin‐induced HeLa‐Luc NDCs (Figure S3G,H, Supporting Information). Here, ATF4 is linked to metastatic neoplasm.