Moreover, the KEGG pathway enrichment analysis also indicated that the DEGs were significantly enriched in immune-related pathways, for example, Th17 cell differentiation, Th1 and Th2 cell differentiation, primary immunodeficiency, IL-17 signaling pathway, and T cell receptor signaling pathway (Fig. 1B and Supplementary Table S3). The gene discussed is IL17A; the disease is inborn error of immunity.