IGF2 and Alzheimer disease: Using ChIP-qPCR analyses with an antibody toward Aβ42 we found that there was significantly greater Aβ42 association with the Igf2 DMR2 sequence containing the potential AβID region in frontal cortex of AD patients than there was with the H19 ICR that did not include this AβID region (Fig. 5b; Table S3).