To evaluate the influence of LONP1 acetylation on tumor growth, SW480 cells stably transfected with vector, LONP1-WT, LONP1-K145Q and LONP1-K145R were xenotransplanted to athymic nude mice (BALB/c-nu/nu) (Fig. 6A). The gene discussed is LONP1; the disease is neoplasm.