To explore the activation status of Wnt/β-catenin signaling in patients with uveitis, we collected PBMCs from healthy controls and patients with acute Vogt–Koyanagi–Harada disease (VKH) and assessed Wnt/β-catenin pathway activation in total PBMCs, CD11c+ DCs, CD3+ T cells, and B220+ B cells. Here, ITGAX is linked to uveitis.