Recently, many new indices derived from the leukocyte count or percentages and albumin, such as NLAR, LAR, and NPAR, have been proposed as prognostic markers, and those indices have proven to be more sensitive than conventional systemic inflammation markers for predicting mortality or other poor outcomes of coronavirus pneumonia, heart failure, hepatitis, cirrhosis, STEMI, and cardiogenic shock. This evidence concerns the gene ALB and heart failure.