We next performed whole genome sequencing (WGS) of pre-tamoxifen Cre+FLT3ITD/ITD tails and post-tamoxifen AML BM cells and FLT3WT/WT tails and pre-pIpC BM of Mx1-Cre:FLT3ITD/ITD AML samples. The gene discussed is MX1; the disease is acute myeloid leukemia.