CFP and acute myeloid leukemia: We first tested whether the leukemic phenotype was associated by a dominant clonal population that expanded and gave rise to AML by generating Scl-CreERT:ConfettiLSL:FLT3ITD/ITD and Scl-CreERT:ConfettiLSL:FLT3WT/WT mice that would randomly express either GFP, YFP, CFP or RFP upon the induction of Cre recombinase, allowing us to trace clonal evolution based on fluorescent marker expression.