In addition, the results from the TISIDB database and GEPIA database demonstrated that the PRR11 in BLCA was positively correlated with the Th2, CD8 + T cells, M2 macrophages, TAM, Treg, NK, neutrophils, monocytes, and the markers of T cell exhaustion, such as PDCD1, TIM3, CTLA4, and LAG3. The gene discussed is CTLA4; the disease is bladder transitional cell carcinoma.