Next, to investigate whether MUC1 regulates tumor metastasis by reprogramming the immune microenvironment, we calculated the ESTIMATE score, immune score, and stromal score according to LIHC from TCGA database, and found that the ESTIMATE score, immune score, and stromal score of the MUC1 high group were higher than those of the MUC1 low group (Fig. 3a). The gene discussed is MUC1; the disease is neoplasm.