For instance, IF is able to increase the expression of some hepatic miRNAs, including miR‐15a, miR‐17, and miR‐29c, and then participates in several metabolic and mitochondrial pathways.[164] IF can inhibit miR‐29a expression and thus suppress lipoprotein lipase, but induce the expression of miR‐130a that directly targets histone deacetylase 3 (HADC3), a marker of AD, resulting in improved brain function and reduced risk for AD.[165, 166] In addition to miRNAs, lncRNAs might contribute to the effects of IF on glucose metabolism and metabolic stress. This evidence concerns the gene HDAC3 and Alzheimer disease.