CREB1 and central nervous system neoplasm: From the CREB family genes, CREB1, CREM and ATF1 are equally distributed (representing 31, 36 and 33% of partner genes respectively) in fusions encountered in IMT [2–36], contrary to other extra-CNS tumors with FET::CREB fusion (like angiomatoid fibrous histiocytomas of the soft tissue having more than 80% of reported cases described with an EWSR1::CREB1 fusion).