On the contrary, we can observe proteins overexpressed in the tumor compared to tumoroids involved in cell growth and maintenance, actin filament-based process (through ACTG1, ACTN1, ARPC2, EZR, FLNA, GSN, MYH11, MYH14, MYH9, MYL6, MYO1C, TLN1, TPM3, VIM), cell communication, signal transduction, and immune response (Fig. 7E). This evidence concerns the gene GSN and neoplasm.