PDE4B and gastric cancer: In this study, we demonstrated that the association of miR-26b-5p with Phosphodiesterase 4B (PDE4B) and Cyclin dependent kinase 8 (CDK8) and STAT3 might provide a possible explanation for the constitutive activation of the STAT3 in GC and provided new insight into the underlying mechanism of inflammation-related GC progression.