Afterwards, multivariable Cox regression analysis revealed that seven cuproptosis-related lncRNAs (NFE4, LINC00989, LINC02062, AC006460.2, AL353796.1, PSMB8-AS1, and AC000120.1) were independent risk factors for AML prognosis (Fig. 2E, Additional file 3: Table S3). This evidence concerns the gene PSMB8 and acute myeloid leukemia.