Afterwards, multivariable Cox regression analysis revealed that seven cuproptosis-related lncRNAs (NFE4, LINC00989, LINC02062, AC006460.2, AL353796.1, PSMB8-AS1, and AC000120.1) were independent risk factors for AML prognosis (Fig. 2E, Additional file 3: Table S3). The gene discussed is NFE4; the disease is acute myeloid leukemia.