The MxA/CRP ratio was significantly higher in patients with viral infections compared to bacterial infections (15.1 [10.1, 36.3] vs. 1.8 [1.1, 3.5]; p < 0.0001) as well as viral-bacterial co-infections (8.8 [1.9, 12.1]; Fig. 3c). This evidence concerns the gene CRP and bacterial infectious disease.