As expected, TET2MUT and TET2/IDHWT patients could show mutations in additional genes frequently observed in MDS/CMML1, including SRSF2 (29% and 3%, respectively), SF3B1 (18% and 20%, respectively) or ASXL1 (18% and 17%, respectively) (Supplementary Fig. 6 and Supplementary Table 5). Here, SRSF2 is linked to myelodysplastic syndrome.