Noninvasive markers of liver cirrhosis including MRE (P < 0.001), Fib-4 (P = 0.17), FibroSure/Fibrotest (P = 0.003), Enhanced Liver Fibrosis test (P < 0.001), hyaluronic acid (P = 0.001), PIII-NP (P = 0.17), and tissue inhibitor of metalloproteinase-1 (P = 0.031) were all elevated in NASH patients with cirrhosis compared to noncirrhotic NASH subjects. Here, TIMP1 is linked to Cirrhosis.