Meta-regression (adjusted for age and COVID-19 severity) showed that being in the ICU (adjusted OR 3·69 [95% CI 1·27–10·68]), receiving IL-6 inhibitors (1·44 [1·03–2·01]), and having diabetes (1·95 [1·19–3·21]) were associated with increased odds of the presence of antibiotic-resistant isolates (table 2). The gene discussed is IL6; the disease is diabetes mellitus.