INS and Insulin resistance: However, it also should be noted that while there were a tendency of decreased insulin signaling in SAT and BAT and modestly elevated plasma insulin levels in FMT-colitis group mice, no significant elevation of fasting blood glucose indicative of insulin resistance was observed (S2F Fig), which indicated that the colonization of fecal microbiota from colitis mice in GF mice caused a disturbance in glucose metabolism, but not so severe that it can be called insulin resistance.