LRRC15 and viral infectious disease: Compared to unmodified CaLu-3 cells that lack any detectable LRRC15, the expression of LRRC15 modestly enhanced viral infection (Fig 4H, MOI 0.005: p = 0.0008, U = 396; MOI 0.05: p = 0.14, U = 580; S28 Data).