Serum tumor markers carcinoembryonic antigen (CEA), carbohydrate antigen 199 (CA199), and carbohydrate antigen 72‐4 (CA724) were originally markers of gastrointestinal and gynecological tumors, but were also significantly elevated in UrC, and their elevation was closely related to their staging and adverse prognosis.20, 21, 22. The gene discussed is CEACAM5; the disease is female reproductive system neoplasm.