Additionally, deletion of Ercc1 in cardiac myocytes induced marked ventricular interstitial fibrosis at 6 months in Ckmm‐Cre+/−;Ercc1−/fl (Figure 2e), consistent with histopathologic changes in dilated cardiomyopathy (Khan & Sheppard, 2006; Li et al., 2018; Schulze, 2009). This evidence concerns the gene ERCC1 and dilated cardiomyopathy.