Consistent with previous studies, METTL3 protein expression was higher in both PCa patient specimens and PCa cell lines compared with non-malignant prostate tissue and cells (Cai et al., 2019; Barros-Silva et al., 2020; Li E. et al., 2020; Yuan et al., 2020; Haigh et al., 2022). This evidence concerns the gene METTL3 and posterior cortical atrophy.