Nuclear CBLL1 expression was higher in patients with a higher Gleason score at diagnosis (p = .031) (Supplementary Table S2) yet, interestingly, lower cytoplasmic CBLL1 expression was observed in PCa patients with concurrent high grade prostatic interepithelial neoplasia (PIN) (p = .037) (Supplementary Table S2). Here, CBLL1 is linked to posterior cortical atrophy.