Differentially expressed protein coding genes and metabolites were enriched in “Cell cycle, “FoxO signaling pathway,” “Oocyte meiosis,” “MAPK signaling pathway,” “Cellular senescence,” “IL-17 signaling pathway.” FOXO1 plays an important role in diabetic cardiomyopathy (34, 35). The gene discussed is FOXO1; the disease is diabetic cardiomyopathy.