By contrast, the expression levels of CDC42 effector protein (Rho GTPase binding) 4b (CDC42EP4b, LOC110499240), armadillo repeat-containing protein 5 (ARMC5, LOC110538625), protein S100-A1 (S100-A1, LOC110520887), phosphatidylinositol 3-kinase regulatory subunit alpha (PIK3R1, LOC110526129), and transcriptional regulator Myc-like (c-Myc, LOC110535641) in the J-IHNV infection group were decreased by 1.32-fold, 2.14-fold, 1.89-fold, 1.33-fold, and 1.51-fold, compared with the U-IHNV infection group (the fold change was represented as log2FC; Supplementary Table 6). Here, PIK3R1 is linked to infection.